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Which the design of homeostasis—or negative comments—can not explain the consequences of frequently administered drugs within a satisfactory way was thoroughly reviewed within a past paper (Peper 2004a).The paper discusses how the event of tolerance to the drug affects the measurement of the dose response curve and signifies the major effects t
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Altogether, these conclusions are all the more substantial provided that the endogenous amounts of L-DOPA are usually taken for a measure of TH activity and the latter is amplified within the brain of α2A and α2CKO mice. Actually, increased L-DOPA tissue amounts inside the adrenal medulla of α2CKO mice are used as an indication of amplified TH e
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